Author: Heinrich, F., Shukla, K., et. al.
Synergistic Biophysical Techniques Reveal Structural Mechanisms of Engineered Cationic Antimicrobial Peptides in Lipid Model Membranes
Publisher: Chemistry - A European Journal, 2020
Abstract
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In the quest for new antibiotics, two novel engineered cationic antimicrobial peptides (eCAPs) have been rationally designed. WLBU2 and D8 (all 8 valines are the d ‐enantiomer) efficiently kill both Gram‐negative and ‐positive bacteria, but WLBU2 is toxic and D8 nontoxic to eukaryotic cells. We explore protein secondary structure, location of peptides in six lipid model membranes, changes in membrane structure and pore evidence. We suggest that protein secondary structure is not a critical determinant of bactericidal activity, but that membrane thinning and dual location of WLBU2 and D8 in the membrane headgroup and hydrocarbon region may be important. While neither peptide thins the Gram‐negative lipopolysaccharide outer membrane model, both locate deep into its hydrocarbon region where they are primed for self‐promoted uptake into the periplasm. The partially α‐helical secondary structure of WLBU2 in a red blood cell (RBC) membrane model containing 50 % cholesterol, could play a role in destabilizing this RBC membrane model causing pore formation that is not observed with the D8 random coil, which correlates with RBC hemolysis caused by WLBU2 but not by D8.
https://doi.org/10.1002/chem.202000212
In the quest for new antibiotics, two novel engineered cationic antimicrobial peptides (eCAPs) have been rationally designed. WLBU2 and D8 (all 8 valines are the d ‐enantiomer) efficiently kill both Gram‐negative and ‐positive bacteria, but WLBU2 is toxic and D8 nontoxic to eukaryotic cells. We explore protein secondary structure, location of peptides in six lipid model membranes, changes in membrane structure and pore evidence. We suggest that protein secondary structure is not a critical determinant of bactericidal activity, but that membrane thinning and dual location of WLBU2 and D8 in the membrane headgroup and hydrocarbon region may be important. While neither peptide thins the Gram‐negative lipopolysaccharide outer membrane model, both locate deep into its hydrocarbon region where they are primed for self‐promoted uptake into the periplasm. The partially α‐helical secondary structure of WLBU2 in a red blood cell (RBC) membrane model containing 50 % cholesterol, could play a role in destabilizing this RBC membrane model causing pore formation that is not observed with the D8 random coil, which correlates with RBC hemolysis caused by WLBU2 but not by D8.
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Author: Kalra, M., Panicker, D., Dixit, A., Jain, R., Thakur, B.
Transgressing International Boundaries: Ensuring Access to Sustainable and Affordable Energy for All
Publisher: In: Encyclopedia of the UN Sustainable Development Goals. Affordable and Clean Energy, 2020
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Author: Agarwal, T., Suravajhala, R., Bhushan, M., Goswami, P., Iddamalgoda, L., Malik, B., Valadi, J, and Suravajhala, P.
Recent Advances in Gene and Genome Assembly: Challenges & Implications
Publisher: In: Singh V. (eds) Advances in Synthetic Biology. Springer, Singapore, 2020
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Thelast decade has seen a surge in genome assembly and sequencing technologies. From the good old DNA sequencing and electrophoresis reads enunciated by Sanger, Maxam, and Gilbert, several tools were embodied through the use of these methods and yet, the challenges these methods imposed have had a paradigm shift. In this focused review, we provide a gist of the tools used by the genome assemblers and discuss the challenges and implications of the next generation sequencing chemistries shaped up by the development of tools.
https://doi.org/10.1007/978-981-15-0081-7_12
Thelast decade has seen a surge in genome assembly and sequencing technologies. From the good old DNA sequencing and electrophoresis reads enunciated by Sanger, Maxam, and Gilbert, several tools were embodied through the use of these methods and yet, the challenges these methods imposed have had a paradigm shift. In this focused review, we provide a gist of the tools used by the genome assemblers and discuss the challenges and implications of the next generation sequencing chemistries shaped up by the development of tools.
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Springer
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SCOPUS®
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Author: Saif-Alyousfi, A.Y.H., Saha, A., Md-Rus, R., and Mohd. K. N. T.
Do oil and gas price shock have impact on bank performance
Publisher: Journal of Commodity Markets, 2020
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The paper examines the impact of oil and gas price shocks on bank performance in the major oil and gas exporting GCC countries, using data for the period 2000–2017. Results indicate that oil and gas price rises have a direct bearing on bank performance through the channel of price-induced bank deposits and related lending to business activities. The negative impact on bank performance due to a drop in oil and gas prices is greater than the positive effect of a rise in prices. Findings suggest that oil and gas price volatility has an asymmetric effect on conventional and Islamic banks. Conventional banks reap more benefit from the increased cash flow created by oil and gas prices, compared to Islamic banks. While Islamic banks are generally vulnerable to adverse oil and gas price shocks, conventional banks tend to benefit more from positive oil and gas price shocks. The association between oil and gas price shocks and bank performance in GCC has been distorted by the global financial crisis, the Arab Spring, and the ongoing Yemen War, which have lowered performance. The findings of the study have significant policy implications for the central banks as well as the governments in the oil and gas-exporting countries.
https://doi.org/10.1016/j.jcomm.2020.100147
The paper examines the impact of oil and gas price shocks on bank performance in the major oil and gas exporting GCC countries, using data for the period 2000–2017. Results indicate that oil and gas price rises have a direct bearing on bank performance through the channel of price-induced bank deposits and related lending to business activities. The negative impact on bank performance due to a drop in oil and gas prices is greater than the positive effect of a rise in prices. Findings suggest that oil and gas price volatility has an asymmetric effect on conventional and Islamic banks. Conventional banks reap more benefit from the increased cash flow created by oil and gas prices, compared to Islamic banks. While Islamic banks are generally vulnerable to adverse oil and gas price shocks, conventional banks tend to benefit more from positive oil and gas price shocks. The association between oil and gas price shocks and bank performance in GCC has been distorted by the global financial crisis, the Arab Spring, and the ongoing Yemen War, which have lowered performance. The findings of the study have significant policy implications for the central banks as well as the governments in the oil and gas-exporting countries.
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ABDC : A
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SCOPUS®
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Q2
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Author: Kalra, N. and Nene, M.
Ethics and Feminist Archiving in the Digital Age: An Interview with CS Lakshmi
Publisher: "Dodd, M and Kalra, N. (Eds) In: Exploring Digital Humanities in India Pedagogies, Practices, and Institutional Possibilities, Routledge India", 2020
Links
https://www.routledge.com/The-Routledge-International-Handbook-of-Global-Therapeutic-Cultures-1st/Nehring-Madsen-Cabanas-Mills-Kerrigan/p/book/9780367110925
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Author: Siddiqui, S.
Faith Healing: Haunted Discourses of Distress in India
Publisher: Nehring, D., Madsen, O.J., Cabanas, E., Mills, C., and Kerrigan, D. (Eds): In The Routledge International Handbook of Global Therapeutic Cultures, 2020
Links
https://www.routledge.com/The-Routledge-International-Handbook-of-Global-Therapeutic-Cultures-1st/Nehring-Madsen-Cabanas-Mills-Kerrigan/p/book/9780367110925
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Author: B. J. Godley, A. C. Broderick, L. P. Colman, A. Formia, M. H. Godfrey, M. Hamann, A. Nuno, L. C. M. Omeyer, A. R. Patrício, A. D. Phillott, A. F. Rees and K. Shanker
Reflections on sea turtle conservation
Publisher: Oryx, 2020
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Why do sea turtles garner such intense interest? The answer is visceral: they are widely loved! A cryptic life cycle spent mostly out of view lends a sense of mystery that makes them special. Yet, these large animals are highly accessible at an extremely vulnerable time, when females emerge on sandy beaches at night to lay eggs, before disappearing again into the oceans. Being nocturnal, they provide us the adventure of going out in the dark on secluded beaches to find them. Plus, the hatchlings are cute, and releasing them into the sea must be one of the most engaging activities that people can do with a protected species.
https://doi.org/10.1017/S0030605320000162
Why do sea turtles garner such intense interest? The answer is visceral: they are widely loved! A cryptic life cycle spent mostly out of view lends a sense of mystery that makes them special. Yet, these large animals are highly accessible at an extremely vulnerable time, when females emerge on sandy beaches at night to lay eggs, before disappearing again into the oceans. Being nocturnal, they provide us the adventure of going out in the dark on secluded beaches to find them. Plus, the hatchlings are cute, and releasing them into the sea must be one of the most engaging activities that people can do with a protected species.
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Author: Thakur, K.
Teaching Print Journalism
Publisher: Vishwakarma Publications, 2020
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Author: Dyondi, R., Jha, S.K. and Haldar, A.
What constitutes risk for a theatrical film distributor? Evidence from the Hindi film industry
Publisher: International Journal of Organizational Analysis, 2020
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This paper aims to examine the strategic issues of risk for independent theatrical film distributors in the Hindi film industry in India.
https://doi.org/10.1108/IJOA-03-2020-2086
This paper aims to examine the strategic issues of risk for independent theatrical film distributors in the Hindi film industry in India.
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ABDC B
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SCOPUS®
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Q3
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Author: Chaudhry, S.
Understanding Change Enablers in Service Organizations: A Contingency Theory Perspective
Publisher: South Asian Journal of Management, 2020
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Author: Goyal, S., Agrawal, A. and Sergi, B.S.
Social entrepreneurship for scalable solutions addressing sustainable development goals (SDGs) at BoP in India
Publisher: Qualitative Research in Organizations and Management, 2020
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The study addresses the crucial issue of sustainable development goals (SDGs) and institutional voids in the peri-urban geographies of India. The peri-urban geographies, though within a cosmopolitical city, lack basic amenities like drinking water, sanitation and waste management. We study social entrepreneurial strategies to address these issues and thereby illustrate strategies that could be used to address sustainable development goals.
https://doi.org/10.1108/QROM-07-2020-1992
The study addresses the crucial issue of sustainable development goals (SDGs) and institutional voids in the peri-urban geographies of India. The peri-urban geographies, though within a cosmopolitical city, lack basic amenities like drinking water, sanitation and waste management. We study social entrepreneurial strategies to address these issues and thereby illustrate strategies that could be used to address sustainable development goals.
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ABDC B
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SCOPUS®
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Q4
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Author: Chaudhuri, Ranjan; Vrontis, Demetris; Chavan, Gitesh; Shms, Riad
Social Business Enterprises as a Research Domain: A Bibliometrics analysis and research direction
Publisher: Journal of Social Entrepreneuership, 2020
Links
https://doi.org/10.1080/19420676.2020.1861477
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ABDC B
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SCOPUS®
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Q1
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Author: Jagani, K., Shinde, S.
Compensatory consumption and reprieve from trauma-related negative emotions: An Indian context
Publisher: International Journal of Marketing Semiotics, 2020
Abstract
Trauma victims experience intense negative emotions during and post-trauma. These negative emotions may last for a long time and disrupt the normal functioning of an individual. Exposure to a traumatic event often leads to a threatened self-identity. The role of compensatory consumption in alleviating negative emotions and protecting from threats to self-identity has been addressed in the extant literature. The present study aims to explore the compensatory consumption behavior of trauma victims that stems from negative emotions and threats to selfidentity. The study also aims to understand the emotional changes and outcomes of this consumption as experienced by traumatized subjects. In-depth interviews were used as the primary data-collection method, aimed at eliciting thick descriptions from the respondents. The findings are discussed with regard to their practical and theoretical implications, as well as potential avenues for future research.
Trauma victims experience intense negative emotions during and post-trauma. These negative emotions may last for a long time and disrupt the normal functioning of an individual. Exposure to a traumatic event often leads to a threatened self-identity. The role of compensatory consumption in alleviating negative emotions and protecting from threats to self-identity has been addressed in the extant literature. The present study aims to explore the compensatory consumption behavior of trauma victims that stems from negative emotions and threats to selfidentity. The study also aims to understand the emotional changes and outcomes of this consumption as experienced by traumatized subjects. In-depth interviews were used as the primary data-collection method, aimed at eliciting thick descriptions from the respondents. The findings are discussed with regard to their practical and theoretical implications, as well as potential avenues for future research.
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Author: Samanta, T
Living solo at midlife: Can the pandemic de-stigmatize living alone in India?
Publisher: Journal of Aging Studies, 2020
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In this piece I argue that the pandemic with its emphasis on social distancing as a desirable civic norm can reconfigure popular understanding of mature female singlehood in India- a condition that is often described in the language of lacks and social failures. The pandemic, I argue, has reaffirmed the everyday practices of upper middle-class professional women (ages 50–60 years) lending them as positive agentic subjects who are invested in self-actualization and an appreciation of intimate solitude. Overall, by specifically focusing on subjectivities and social aspirations of my interlocutors during the pandemic, I illuminate ways in which middle aged selfhood is lived in all its fragility, ambivalence and emergent possibilities.
https://doi.org/10.1016/j.jaging.2020.100907
In this piece I argue that the pandemic with its emphasis on social distancing as a desirable civic norm can reconfigure popular understanding of mature female singlehood in India- a condition that is often described in the language of lacks and social failures. The pandemic, I argue, has reaffirmed the everyday practices of upper middle-class professional women (ages 50–60 years) lending them as positive agentic subjects who are invested in self-actualization and an appreciation of intimate solitude. Overall, by specifically focusing on subjectivities and social aspirations of my interlocutors during the pandemic, I illuminate ways in which middle aged selfhood is lived in all its fragility, ambivalence and emergent possibilities.
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Author: Rooj, D., and Sengupta, R.
A Multivariate Bayesian Vector Autoregression Analysis of Digital Payment Systems and Economic Growth in India
Publisher: In: Beirne, J. and Fernandez, D.G. (Eds). Macroeconomic stabilization in the digital age, 2020
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Author: Viraj Shah
Rock-cut Caves of Western India
Publisher: in Dilip Chakrabarti ed. History of Ancient India- VIII: Sculpture, Painting, Terracottas, Performing Arts and Architecture, New Delhi: Vivekananda International Foundation/Aryan Books International , 2020
Links
https://www.vifindia.org/book/2020/march/27/history-of-ancient-india-viii
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Author: Malhotra, M., Ghura, A.S., Thakur, B.S.
InterGlobe Aviation Limited : Need for Strategy
Publisher: Emerald Market Case Studies, 2020
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This case describes a situation in which InterGlobe Aviation Ltd. (IGAL) has been experiencing multiple engine snags because of the faulty Pratt and Whitney engines. In a span of two years between June 2018 and January 2020, IGAL faced around 22 snags. IGAL is known to be one of the safest airlines in the world, the engine issue has tainted its reputation. In October 2019, in just one week IA faced four-engine snags, forcing the Directorate General of Civil Aviation (DGCA) to come out with a guideline in November 2019. The faulty engines were to be replaced by January 31, 2020. If IA failed to complete the task by the given deadline then IA would have to ground around 70–80 aircraft. IA was way behind the deadline when on January 13, 2020, they received an email from DGCA mentioning an extension of the deadline to May 31, 2020. The purpose of this case is to provide an opportunity for the participants to take into consideration the data given for IA and make assumptions and resolve the dilemma through which Ronojoy Dutta (Dutta), the Chief executive officer if IA is going through.
https://doi.org/10.1108/EEMCS-07-2020-0280
This case describes a situation in which InterGlobe Aviation Ltd. (IGAL) has been experiencing multiple engine snags because of the faulty Pratt and Whitney engines. In a span of two years between June 2018 and January 2020, IGAL faced around 22 snags. IGAL is known to be one of the safest airlines in the world, the engine issue has tainted its reputation. In October 2019, in just one week IA faced four-engine snags, forcing the Directorate General of Civil Aviation (DGCA) to come out with a guideline in November 2019. The faulty engines were to be replaced by January 31, 2020. If IA failed to complete the task by the given deadline then IA would have to ground around 70–80 aircraft. IA was way behind the deadline when on January 13, 2020, they received an email from DGCA mentioning an extension of the deadline to May 31, 2020. The purpose of this case is to provide an opportunity for the participants to take into consideration the data given for IA and make assumptions and resolve the dilemma through which Ronojoy Dutta (Dutta), the Chief executive officer if IA is going through.
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Author: Parida, Y., and Chowdhury, J.R
An empirical analysis of the effect of floods on rural agricultural wages across Indian states
Publisher: World Development Perspectives, 2020
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This study employs a Pooled Mean Group (PMG) estimation method to examine the effect of floods on rural agricultural wages, controlling for key wage determinants for 15 major Indian states over the period 1983–2011. The PMG estimates suggest that damages due to floods have a positive impact on annual agricultural wages and agricultural wages in flood months in the long run but an adverse effect in the short run. In other words, our findings indicate that annual agricultural wages and agricultural wages in flood months increase by 0.164 percent and 0.149 percent, respectively, in the long run, but they decline by 0.025 percent and 0.026 percent, respectively, in the short run when damages due to floods increase by 10 percent. Moreover, we find that better employment opportunities in rural non-agricultural sectors significantly increase agricultural wages in the long run. Our empirical findings are robust to alternative flood measures in terms of area affected by floods. In sum, we conclude that floods have differential impacts on agricultural wages in the short and long run, after taking into account the key wage determinants.
https://doi.org/10.1016/j.wdp.2020.100272
This study employs a Pooled Mean Group (PMG) estimation method to examine the effect of floods on rural agricultural wages, controlling for key wage determinants for 15 major Indian states over the period 1983–2011. The PMG estimates suggest that damages due to floods have a positive impact on annual agricultural wages and agricultural wages in flood months in the long run but an adverse effect in the short run. In other words, our findings indicate that annual agricultural wages and agricultural wages in flood months increase by 0.164 percent and 0.149 percent, respectively, in the long run, but they decline by 0.025 percent and 0.026 percent, respectively, in the short run when damages due to floods increase by 10 percent. Moreover, we find that better employment opportunities in rural non-agricultural sectors significantly increase agricultural wages in the long run. Our empirical findings are robust to alternative flood measures in terms of area affected by floods. In sum, we conclude that floods have differential impacts on agricultural wages in the short and long run, after taking into account the key wage determinants.
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Author: Damani, C., Damani, B., Bagchi, A.
Match statistics significant to win in initial and intense rounds of a tennis tournament
Publisher: Trends in sports sciences, 2020
Abstract
This paper analyses the initial and intense rounds of the 2020 Australian Open Men’s Singles matches on 14 match statistics. The findings show that the statistics which are important to winning in the initial rounds are not the same as those for winning in the intense rounds. In the initial rounds, the match winner performed better than the loser on receiving points won, second serve to win, first serve to win, breakpoints won, net points won, winners, total points won, unforced errors, aces, double faults, fastest serve speed, and average first-serve speed. However, to win the intense rounds, the winner performed better than the loser on first serve to win, receiving points won and net points won. The findings help the player and the coach to develop skills and techniques to devise a player strategy during the initial rounds and the intense rounds to win the tournament
This paper analyses the initial and intense rounds of the 2020 Australian Open Men’s Singles matches on 14 match statistics. The findings show that the statistics which are important to winning in the initial rounds are not the same as those for winning in the intense rounds. In the initial rounds, the match winner performed better than the loser on receiving points won, second serve to win, first serve to win, breakpoints won, net points won, winners, total points won, unforced errors, aces, double faults, fastest serve speed, and average first-serve speed. However, to win the intense rounds, the winner performed better than the loser on first serve to win, receiving points won and net points won. The findings help the player and the coach to develop skills and techniques to devise a player strategy during the initial rounds and the intense rounds to win the tournament
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Author: B.K.Thakur, B.K., Gupta, V., Bhattacharya, P., Jakariya, Md., and Islam, Md.
Arsenic in drinking water sources in the Middle Gangetic Plains in Bihar: An assessment of the depth of wells to ensure safe water supply
Publisher: Groundwater for Sustainable Development, 2020
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This study assesses the depth of tubewell and the associated concentration of arsenic (As) in drinking water within the arsenic-affected regions in Bihar, India. A survey of 935 tubewell from two As-contaminated blocks in Bihar were conducted to collect and test the water samples. The results demonstrate that As concentration is mainly found in shallow tubewells (14–49 m deep), which is the main source of drinking water in the region in deep tubewells (>49 m deep), have arsenic concentration er contamination and its associated health impacts. Therefore, awareness through various channels among the affected stakeholders will be helpful for the households to change their water sources (Saha et al., 2018, 2019).
https://doi.org/10.1016/j.gsd.2020.100504
This study assesses the depth of tubewell and the associated concentration of arsenic (As) in drinking water within the arsenic-affected regions in Bihar, India. A survey of 935 tubewell from two As-contaminated blocks in Bihar were conducted to collect and test the water samples. The results demonstrate that As concentration is mainly found in shallow tubewells (14–49 m deep), which is the main source of drinking water in the region in deep tubewells (>49 m deep), have arsenic concentration er contamination and its associated health impacts. Therefore, awareness through various channels among the affected stakeholders will be helpful for the households to change their water sources (Saha et al., 2018, 2019).
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